Microneedling
Microneedling
Microneedling (MN) is a novel therapeutic modality in dermatology. Through physical trauma from needle penetration, MN induces a wound healing cascade with minimal damage to the epidermis. This allows for enhancement in the absorption of mainstay topical therapies across the thick stratum corneum. MN has become increasingly utilized over the last several years as it is a relatively simple procedure that is cost-effective, well tolerated, and offers both cosmetic and therapeutic benefits.
The ability to treat localized areas of disease has led to numerous studies gauging its potential in focal diseases of inflammation, dyschromia, and photodamage. This review discusses the principles and evidence behind the expanding applications of MN. It has shown promising results as an adjuvant therapy for enhanced drug delivery in the treatment of atrophic scars, alopecia, actinic keratoses, and disorders of pigmentation such as melasma.
Introduction
Microneedling (MN), also known as collagen induction therapy, is a process involving repetitive puncturing of the skin with sterilized microneedles. Its original conception can be traced back to 1995, when Orentreich and Orentreich developed the concept of “subcision”, or using hypodermic needles to induce wound healing in depressed cutaneous scars.
MN offers a relatively low cost and minimally invasive tool for the treatment of multiple cosmetic and dermatologic conditions.3 The basis of MN relies on physical trauma. It has been proposed that the trauma generated by needle penetration in the skin induces regeneration of the dermis
Methods
The studies selected for this review were gathered by searching the PubMed, MEDLINE, Cochrane databases, and electronic journals of dermatology. The search terms used for this review included “microneedling”, “collagen induction”, “reviews”, and “trials”. Only articles published in English were considered for inclusion in this review.
Articles were obtained in all circumstances and references were checked for additional information when considered applicable. Available studies involving human subjects were included in the review. Additionally, only studies regarding manual MN techniques were considered for inclusion.
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